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电影根据蕾切尔·约德的同名小说《夜母》改编，原作入围了美国笔会/海明威奖。讲述了一位新晋为母亲的女性艺术家，在全职照顾孩子时越发孤独焦虑的故事。在她眼里，自己从来都不是一个母亲，既然现在成了母亲，就一定要成为快乐的那个。经过多番努力与尝试后，她发现只有变身母狗可以实现这一愿望。
在瑞士一家医院的外科病房工作的Floria（Leonie Benesch饰）是一位充满热情与专业精神的外科护理师。她技术娴熟，即使在压力巨大的情况下也总能耐心倾听每一位病人的需求，在紧急情况下，她总能迅速到场——理想状态下是如此。然而现实情况中这份工作常常难以预料，情况远没有那么理想。
这一天，Floria开始了她的晚班，但在这个床位已满、人手紧缺的病房里一位同事突然因故缺勤。尽管工作繁忙，她仍尽心照顾着一位重病的母亲（Lale Yavas饰）和一位焦急等待诊断的老人（Urs Bihler饰），同样细致周到地应对着那位私人病人（Jürg Plüss饰）的各种额外要求。
然而，一场致命的错误悄然发生，让整个值班陷入混乱。一场与时间赛跑的紧张之旅由此开始。
An old woman, Filomena, is hurried into the emergency room. The young man, who brought her, Matias, is very nervous. The nurses were drawn to him as he’s very good-looking. They think he’s her grandson. Filomena’s condition has stabilized but she needs further tests. At night, Matias visits her and Luna, the nurse on duty, is touched at how warm and close Matias is to the lady. Then Luna finds out something surprising yet heartbreaking-Filomena and Matias are lovers. Matias is a vampire whom Filomena when she was young. Their love was uncontrollable. Matias promised Filomena that he will not give her the curse of being a vampire- even if Filomena wants to be with him forever. Now that death is in the middle of their love, will Matias broke the vow so that they can continue their unconditional love forever? Will he allow death to take the woman that he loves? Luna in the end learns one of the greatest lessons about love and sacrifice.
