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在上一季中，以果敢干练的作风和高超惊人的医术，人称 “Doctor X”外科医生大门未知子（米仓凉子 饰）在早已形同腐臭泥潭一般的帝都医科大学第三医院力挽狂澜，掀起前所未有的风暴。因在北海道马场冒险为一匹骨折的马做手术，未知子得到内科专家马渊一代（三田佳子 饰）的赏识，进而受邀踏入全日本顶尖医者云集的殿堂——帝都医科大学附属医院！此前不久，外科总负责人蛭间重盛（西田敏行 饰）曾亲手为医院的大金主——某地产大鳄二宫钦也（寺田农 饰）完成高危手术，谁知此番二宫癌症复发再度入院。第二外科主任海老名（远藤宪一 饰）携团队积极备战，配合蛭间迎接新一轮的手术。而马渊所率领的内科则就治疗方式上与外科产生严重分歧和对立。
未知子的到来，无疑使双方的矛盾趋于白热化……
本季喜剧人：Sarah Silverman、David Letterman、Gad Elmaleh、Don Rickles、Seth Meyers、Chris Rock。
After an embarrassing and meijubar.net public breakdown, Detective Aidan Black (David Sutcliffe) is reassigned from his beloved SWAT team to the newly created Psych Crimes and Crisis Unit. There, he's dismayed to find his partner is not another cop, but forensic psychiatrist, Dr. Daniella Ridley (Stefanie von Pfetten). The unit also includes Detective Poppy Wisnefski (Luisa d'Oliveira) and psychiatric nurse Leo Beckett (Dayo Ade), with Inspector Diane Caligra (Karen LeBlanc) keeping a close watch over the unique partnerships. Passionate and opposing viewpoints are an inherent part of the job in Psych Crimes, and the answers the teams seek never come easy. Aidan's deep insight and investigative skills combine brilliantly with Daniella's keen ability to decipher human behaviour. Learning to work cohesively, the Psych Crimes and Crisis Unit investigates city's most troubling and psychologically complex crimes. Whether or not the unit is still around in a few months...
After an embarrassing and public breakdown, Detective Aidan Black (David Sutcliffe) is reassigned from his beloved SWAT team to the newly created Psych Crimes and Crisis Unit. There, he's dismayed to find his partner is not another cop, but forensic psychiatrist, Dr. Daniella Ridley (Stefanie von Pfetten). The unit also includes Detective Poppy Wisnefski (Luisa d'Oliveira) and psychiatric nurse Leo Beckett (Dayo Ade), with Inspector Diane Caligra (Karen LeBlanc) keeping a close watch over the unique partnerships. Passionate and opposing viewpoints are an inherent part of the job in Psych Crimes, and the answers the teams seek never come easy. Aidan's deep insight and investigative skills combine brilliantly with Daniella's keen ability to decipher human behaviour. Learning to work cohesively, the Psych Crimes and Crisis Unit investigates city's most troubling and psychologically complex crimes. Whether or not the unit is still around in a few months...
供职于某世界五百强公司的白领丽人简宁（小宋佳 饰）和在机场担任话务员的江心（陈思成 饰）是一对八零后小夫妻，对待事业的态度颇有些不同的二人，生活中即将迎来一个新生命。可是这个小家伙不仅牵涉了夫妻大量的精力，还影响左右着他们的工作以及和家人、朋友、同事的人际关系，令这对小夫妻颇为挠头。简宁的妹妹简艾（万茜 饰）偶然“拾到”来自韩国的女孩乐乐（岛田瑠那 饰），乐乐的父亲严道信（王耀庆 饰）正准备展开一段新的婚姻，对于这个意外到来的女儿甚为苦恼，而与乐乐感情渐深的简艾夜身不由己卷入“他人”的家务事中。简艾的闺蜜赵晓柔（王思思 饰）和恋人吴迪（彭冠英 饰）好不容易修成正果，面对那忽闪着纯真眼睛的小生命，这对扬言不生养的前卫夫妻也受到动摇。
这是一段关于大孩子和小孩子们的生活奏鸣曲……
